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REFLECTIONS
                                                                                                                   Dyslipidaemia
     Dyslipidaemia Global Newsletter #8 2024


         10. Efficacy of combination therapy with statin and ezetimibe versus high dose statin monotherapy in secondary
             prevention in high-risk patients. Halatiu VB, et al. Eur Heart J, Vol 45 (Suppl 1): ehae666.2842      Dyslipidaemia

     SMALL TRIALS, TRIAL UPDATES, AND OTHER STUDIES ON LIPID THERAPY

         11. Cardiovascular efficacy of evolocumab in patients with obesity: Updates from the FOURIER trial. Kang Y, et al.
             Presented Sept 2, 2024 at the ESC Conference

         12. Alternative LDL cholesterol lowering strategy vs. high-intensity statin strategy: An individual patient data meta-
             analysis from the randomized RACING and LODESTAR trials. Hong M, et al. Presented at the 2024 ESC Conference

     LIPIDS AS RISK FACTORS AMONG DIFFERENT POPULATIONS

         13. Patient reported outcomes, control of hypertension and dyslipidemia: Results of two epidemiological studies in
             Romania, conducted during pandemia (Snapshot-1) and post-pandemic (Snapshot-2). Ciobanu A, et al. Eur Heart J,
             Vol 45 (Suppl 1): ehae666.2643




     ACRONYMS:
     ANOCA, angina with non-obstructive coronary arteries; ASCVD, atherosclerotic cardiovascular disease; ASO, antisense
     oligonucleotide; BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; CCS, chronic coronary syndrome;
     CCTA, coronary computed tomography angiography; conc., concentration; CI, confidence interval; CRP, c-reactive protein; CV,
     cardiovascular; CVD, cardiovascular disease; ECG, electrocardiogram; ED, emergency department; EZE, ezetimibe; FCT, free
     combination treatment; FH, familial hypercholesterolaemia; GDMT, guideline-directed medical therapy; GLP-1, glucagon-like
     peptide-1, HoFE, homozygous familial hypercholesterolaemia; HR, hazard ratio; INOCA, ischaemia with non-obstructive coronary
     arteries; IR, incidence rate; LDL-C, low-density lipoprotein-cholesterol; Lp(a), lipoprotein(a); MI, myocardial infarction; NA, not
     applicable; PCSK9i, proprotein convertase subtilisin/kexin type 9 inhibitor; PDC, Proportion of Days Covered; ROS, rosuvastatin;
     SiRNA, small interfering ribonucleic acid; TC, total cholesterol; TG, triglycerides.







































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