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REFLECTIONS

                                                                                                              Dyslipidaemia
     Dyslipidaemia Global Newsletter #8 2024



                  TABLE OF CONTENTS


            KEY ARTICLES                                        Welcome back to the Reflections Dyslipidaemia Global Newsletter,
                                                                where an international Scientific Planning Committee summarizes
          GUIDELINES AND REVIEWS                                and provides expert commentary on the latest clinical and real-
          2024 ESC Guidelines for the management of chronic     world evidence in the field of dyslipidaemia. These articles are
          coronary syndromes. Vrints C, et al. Eur Heart J. 2024 Aug   chosen based on their significance to every day clinical practice.
                                                                                                              Dyslipida
          30:ehae177. doi: 10.1093/eurheartj/ehae177. Online ahead of print.   This newsletter focuses on the new 2024 ESC Guidelines for
          Inflammation, cholesterol, lipoprotein(a), and 30-year   CCS, along with a few interesting review articles on biomarkers
          cardiovascular outcomes in women. Ridker PM, et al. N Engl   and risks of CV, a real-world analysis of adherence and outcomes
          J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2405182. Online ahead
          of print.                                             in patients taking a single-pill combination vs. free combination
          Lipoprotein(a) and cardiovascular disease. Nordestgaard   of rosuvastatin and ezetimibe, a cohort study focused on
          BG, Langsted A. Lancet. 2024 Sep 12:S0140-6736(24)01308-4.   combination statin/ezetimibe vs. high-intensity statin monotherapy
                                                                on CV outcomes, and a clinical consensus statement from the
          TREATMENT                                             National Lipid Association focused on dyslipidaemia in women of

          A real-world analysis of adherence, biochemical outcomes,   reproductive age. We are also pleased to share our Conference
          and healthcare costs in patients treated with rosuvastatin/  Corner, where we highlight some abstracts of interest from the
          ezetimibe as single-pill combination vs. free combination   recent 2024 ESC Congress which took place in London, England.
          in Italy. Zambon A, et al. Eur Heart J Open. 2024 Aug   As with the previous newsletters, we invite you to interact through
          28;4(5):oeae074.                                      links to short video commentaries from our SPC, links to videos
          Combination of low- or moderate-intensity statin and   or podcasts, along with hyperlinks to full articles for in-depth study
          ezetimibe vs. high-intensity statin monotherapy on primary   and reflection.
          prevention of cardiovascular disease and all-cause death:
          a propensity-matched nationwide cohort study. Jun JE, et al.   Prof. Farnier (Chair)
          Eur J Prev Cardiol. 2024 Aug 9;31(10):1205-1213.
          SPECIAL POPULATIONS – WOMEN OF                        SCIENTIFIC PLANNING COMMITTEE
          REPRODUCTIVE AGE
          Dyslipidemia management in women of reproductive             Prof. Michel Farnier        Prof. Augusto Lavalle
          potential: An expert clinical consensus from the national    (France)                    Cobo
                                                                                                   (Argentina)
          lipid association. Agarwala A, et al. J Clin Lipidol. 2024 May
          30:S1933-2874(24)00188-0.
                                                                       Prof. Miriam Sandin         Prof. Lourdes Santos
             ADDITIONAL ARTICLES OF INTEREST                           (Spain)                     (Philippines)

          CONFERENCE CORNER
          Highlighted abstracts of interest from the ESC 2024
          conference                                                   Prof. Ahmed Shawky          Prof. Marcin Welnicki
                                                                       (Egypt)                     (Poland)



    GUIDELINES AND REVIEWS


     2024 ESC Guidelines for the management of chronic coronary syndromes.
     Vrints C, et al. Eur Heart J. 2024 Aug 30:ehae177. doi: 10.1093/eurheartj/ehae177. Online ahead of print.

     The European Society of Cardiology have updated their clinical guidelines for the management of chronic coronary syndromes
     (CCS). These guidelines update and replace the previous version from 2019 and partly replace the myocardial revascularisation
     guidelines from 2018. They outline a stepwise approach to the diagnosis and treatment of CCS, a spectrum of heart conditions
     caused by narrowing or blockage of the coronary arteries.
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